As if its dramatic COVID-19 storylines weren’t enough, the medical drama also bid farewell to three series regulars during Season 17. The first, Andrew DeLuca (Giacomo Gianniotti) was shockingly murdered midway through the season while attempting to chase down a child trafficker. The second, Jackson Avery (Jesse Williams) bid farewell to Grey Sloan Memorial Hospital on his own terms, resigning from his position as Chief of Plastic Surgery at the Seattle hospital in order to travel to Boston and head up his family’s multi-million dollar foundation, with his ex-wife April (Sarah Drew) and their daughter Harriet in tow. There, Jackson hoped to revolutionize the world of modern medicine, bringing affordable and equitable healthcare to marginalized communities. Inspired by Jackson’s vision, recovered COVID patient Tom Koracick (Greg Germann) impulsively decided to jump ship and join him, hoping to find meaning through helping others. So after all that, who’s left in the main Grey’s Anatomy cast going into Season 18, and where are they in their storylines? And will the doctors of Grey Sloan Memorial be visited by any more fan favorites from seasons past? Scroll through our gallery to see everyone we know (or strongly believe!) will appear in the cast of Grey’s Anatomy Season 18. Next, don’t miss the return of any of your favorite shows this fall with our complete Fall TV lineup!
